A simple head-mountable LED device for chronic stimulation of optogenetic molecules in freely moving mice.
نویسندگان
چکیده
We describe a low-cost, small, remotely triggerable LED device for wireless control of transcranial optical stimulation of cortical neurons, for use in freely moving mice. The device is easily mountable on the head of a mouse with a high-polymer block. Using the Thy1-ChR2-YFP transgenic mice, we demonstrate that the device is capable of remotely triggering muscle twitches upon activation of the primary motor cortex in freely moving conditions.
منابع مشابه
Programmable wireless light-emitting diode stimulator for chronic stimulation of optogenetic molecules in freely moving mice.
We produced a miniaturized, multicode, multiband, and programmable light-emitting diode (LED) stimulator for wireless control of optogenetic experiments. The LED stimulator is capable of driving three independent LEDs upon reception of an infrared (IR) signal generated by a custom-made IR transmitter. Individual LED photopulse patterns are assigned to different codes of the IR signals (up to 25...
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عنوان ژورنال:
- Neuroscience research
دوره 70 1 شماره
صفحات -
تاریخ انتشار 2011